Showing posts with label Population Genetics. Show all posts
Showing posts with label Population Genetics. Show all posts

Saturday, March 10, 2012

Speciation + Evolution = LOTS of Trait Diversity with LOSS of Genetic Diversity leading to end of ability to evolve

Another one from RAZD at EvC, Speciation + Evolution = More Diversity
The scene: sitting at computers all over the world ...
"Why don't creationists understand evolution -- it is so simple," the evolutionist wails:

1. Evolution - the change in hereditary traits in populations from generation to generation - is an observed and documented fact, a process that occurs constantly in the natural world around us, and

2. Speciation - the division of parent populations into reproductively isolated daughter populations - is also an observed and documented fact, a process that occurs frequently in the natural world around us.
These two simple processes are sufficient to explain the diversity of life we know, from the world around us, from history, from prehistory and archeology, from geology and physics and paleontology and the fossil record, and from chemistry and the genetic record.
Well, it sounds good on paper, I guess, as theory at least, but unfortunately it fails in reality. Yes, there is an "evolution" by which heritable traits change from generation to generation, but this has never been observed beyond what we call "micro" evolution, or evolution within the genetic limits that define each species, and in fact it can't occur beyond microevolution for the reasons I've given over and over here, which are the same reasons there is no evolution beyond speciation. And yes, speciation is also a documentable fact, but it always occurs with loss of genetic diversity, even to the extreme of fixed loci or total homozygosity for some traits in the population, which makes further evolution beyond speciation purely a pipe dream.

But RAZD just goes on asserting the theory, the pipe dream, as if it were reality, as they all do.
We can even see how evolution causes speciation with Ring Species:

1. the species forms a band made up of several varieties around some barrier to their survival ability,

2. each of the varieties has slightly different hereditary traits from their neighbors,

3. each reproduces with their neighbors in hybrid zones that show a mixing of the hereditary traits of the two neighbors, except that

4. when they meet on the other side of the barrier, the two ends do not mate.

Evolution results in different hereditary traits developing in each of the areas dominated by the different varieties, differences that do not hinder mating until they reach a certain threshold - the difference between the end varieties.

Yes, pretty much but as long as he sticks to the level of traits -- of the phenotypes, of the different observable characteristics between the populations -- he misses the reason what happens happens: The splitting of the populations changes the gene frequencies. When new traits emerge this is because alleles for competing traits have been reduced which can proceed after many population splits to the point that they are completely lost to the new population. After a series of splits the genetic diversity may be quite drastically reduced, and the main reason there is no interbreeding between the first and last populations is the genetic incompatibility that has developed by then.

Again, my prediction is that if you sampled the DNA of the first and last populations (better done in a laboratory where you can sample the first before it too undergoes change), you should find much greater genetic diversity in the first and much reduced diversity in the last, more heterozygosity in the first, more homozygosity in the last, particularly for the traits that are most characteristic of the populations.
Remove any one of the intermediate varieties, so that the band is broken, and you have two distinct species.
We now have more species than before, so life is more diverse. It is so simple:

Evolution + Speciation = Diversity
Way TOO simple, RAZD. Yes you do have more diversity of TRAITS, but you are simultaneously getting REDUCED diversity of GENETIC POSSIBILITIES. This is all just the usual evolutionist daydream based on surface facts completely ignoring what is going on genetically, which is the NECESSARY reduction of genetic diversity, which occurs with EACH splitting off of a portion of the population to form a new population. This is a trend that can keep producing new phenotypes for some time by losing more alleles, but can ultimately arrive at such genetic depletion that no further phenotypic change is possible, a condition like that of the cheetah. Not that this degree of depletion is inevitable, but reduction in that direction certainly is.
This little scenario depicts, I believe, the state of many debates between creationists - people that predominantly use faith to understand the world - and "evolutionists" - people that predominantly use science to understand the world.
What "this little scenario" actually depicts is evolutionist reliance on wishful thinking as they spell out what they THINK happens, because they haven't really faced the GENETIC PICTURE which is working against their all-too-sanguine expectation that change in traits can just go on and on without genetic cost. It really is a daydream, a fantasy. And it's quite the joke that they are constantly claiming to appeal to EVIDENCE and accusing creationists of relying only on faith.

(I skipped his caricature of the creationist response to the above because it is a distraction from what I'm trying to say here.)
Where does "large" change come from? - the change that makes giraffes so different from kangaroos? Simple:

Speciation - the division of parent populations into reproductively isolated daughter populations - is also an observed and documented fact, a process that occurs frequently in the natural world around us, and

Evolution- the change in hereditary traits in populations from generation to generation - is an observed and documented fact, a process that occurs constantly in the natural world around us.
SO simple as long as he just goes on daydreaming about the surface traits and imagining that there are no limits to change.
Speciation + Evolution = More Diversity
After speciation has occurred, the daughter populations no longer share genes through reproduction, and they are free to evolve completely different traits.
Yes, and this lack of sharing of genes means a LOSS OF GENETIC DIVERSITY. Yes, they ARE "free to evolve copletely different traits" but this is ALWAYS made possible by the loss of competing alleles for those traits, which is completely ignored by evolutionists. You can always get new traits BY LOSING competing alleles, but if the population splits that bring this about continue to occur, eventually a point will be reached where you can't get new traits any more because you'll be completely out of alleles. Speciation may not always mean genetic depletion but it certainly means genetic reduction from earlier populations particularly where the main new traits are emerging.
The likelyhood is high that one of them will become quite different, either to inhabit a new ecology that the other is not as well suited to (could have caused the original split), or to make use of the existing ecology in a different way, and this will lessen competition between the two species rather than drive one to extinction.
Lotta sheer conjecture there. It really isn't even necessary to posit environmental or situational reasons for trait changes or even the population splits themselves. Migration will bring about splits and the splits alone will bring about trait changes. The fewer individuals at the start of a new population the bigger the observable trait changes, the ecology is not likely to have much to do with it. It may be that both populations still have sufficient genetic variability even to undergo several further splits if necessary, but since he's completely ignored the whole question of what happens to the genes while focusing on the traits and fantasizing endless change he's going to miss the state of genetic depletion also when it does finally occur after more population splits.
Continued evolution of daughter populations along different ecological paths results in increased diversity - difference - between them over time. That is how the small amount of difference we seen below can become the amount of difference we see between other bird species.
Again, overrated influence from the environment but this is really a side issue, but anyway, the increased diversity is completely the result of the change in gene frequencies brought about by the population split. If the environment contributes an influence that further impacts the population numbers or reproductive isolation and therefore the gene frequencies, then it will contribute to the trait differences between the populations as well, but again, there is no need for this to happen in order for even great differences to come about as the change in gene frequencies alone will do it.
Continued evolution causes more change - in each population, from generation to generation to generation
Along with change in gene frequencies which can rapidly reduce and even eliminate some alleles as the changes continue, to the point that you run out of alleles for enough traits that further change is impossible, probably a very interesting new population with new traits but no more genetic variability.
That should be enough for starters. There is more to discuss about where change occurs, but this is long enough for now. This thread is about evolution after speciation.
A total pipe dream I'm afraid, as speciation is most likely to occur at the very outer edges of the genetic variability of the species, thus preventing further evolution.

Saturday, March 3, 2012

The Creation Model explains the facts quite nicely

We're talking a different whole model here, one that is at least as consistent with the facts as evolutionism. At least.

In the creation model I always have in the back of my mind (some of which I certainly got from creationist sources but some is my own or at least my own way of organizing the material), species are defined at the genetic level by a particular genetic endowment that was built in at creation.

DEFINING THE ORIGINAL SPECIES, ALSO KNOWN AS THE KIND:
In the debate the evolutionists insist that creationists give a definition of a Kind or of microevolution versus macroevolution, which is of course difficult. I've given my dynamic definition of it many times and a test for it as well -- there should be measurably reduced genetic diversity after a series of population reductions as in a ring species, showing the outer limits of the Kind beyond which further evolution is impossible. But I note that Percy/Admin at EvC was apparently trying to reduce the haranguing on the subject in one thread recently by trying to give a brief definition. I think he meant to say that a change from a gray squirrel (population) to a red squirrel (population) is MICROevolution but in fact he said MACROevolution which destroyed his intent, and if so I'd have to agree with that. In general I think if you're inclined to call it by the same name as its predecessor, a "squirrel" in this case, you're talking about MICROevolution. I'm sure there are exceptions but this is most likely the rule. When you're talking about a change from a reptile to a bird or a worm to a human or an ape to a human you're talking MACROevolution.

The original genomic endowment of each species has a great deal of variability built into it that defines the limits of change available to the species, that is, there were many alleles that change the effect of particular genes, originally many more than continue today, and there were many more genes, even many for a particular trait as well, many more than today (They are all now junk DNA, but I get ahead of myself).

This is sufficient for great variability of the species as populations split off from each other down the generations.

VARIATION OR "EVOLUTION" REDUCES GENETIC DIVERSITY
Over time the variability is inevitably reduced by these splittings and isolations for any given population, but the original genetic complement was so rich that the variability remains high for many generations and it's very rare that a particular line of variation gets to the point of allelic depletion for many gene loci, such as happened with the cheetah, but it would happen occasionally with severe bottlenecks -- though originally it would have taken many bottlenecks to reduce the variability to the extent of the cheetah -- and would happen over many generations with many less drastic population splittings as well.

SOME EXAMPLES OF VARIABLES THAT WERE BUILT IN:
Among the original built-in variables for most creatures could be size differences from as big as an elephant to as small as a mouse, as big as a sabertoothed tiger but as small as a housecat, as big as a dinosaur, as small as a lizard. All within the same species. Size and shape of features and limbs would also have a fair degree of variability. Color and patterns of skin or fur or scales also. Length of fur. The excess skin of the Shar Pei is most likely also a built-in variable, one that would probably take many generations of population isolation (nature does it randomly but domestic breeding does it intentionally) to emerge according to this creationist model.

SPECIATION
So: Many variations develop from the original created Species over generations, forming new populations with their own peculiar characteristics, often to the point of "speciation" or cessation of interbreeding with former populations. Speciation in this model is simply what happens when a particular line of variation -- either by random population splitting in nature or intentional splitting by domestic breeding -- has produced a population whose genetic diversity is sufficiently reduced, or whose gene pool has become sufficiently inbred, to prevent breeding of its members with those of the population from which it originally split off. Of course breeding may cease between the two before a genetic reason for it exists, simply because of preference of members of a population for members of the same population. The effect is the same: the separate characteristics of the separated populations are preserved and so are their separate gene pools.

You NEVER get a new "species" in the sense of the original Species or Kind by any of these processes of variation, only variations on the theme of the original Species itself, but they are quite wonderfully many and diverse. So while what is called "speciation" by evolutionists clearly does happen, it's nothing more than a variation that no longer interbreeds with the rest of its Kind, so that its own pecular characteristics are preserved.

As such variations inbreed and become established in their own niches they refine their own gene pool and that further cuts them off from other members of the species.

MUTATIONS
In this model, mutations are mistakes or accidents brought about by the Fall. They have no positive function in the organism, only a negative or destructive one. They may produce no identifiable change at all, but only because the original DNA is not easily damaged. But the fact that they change anything at all in the originally perfect genetic design makes them a disease process.

Whenever I read a description of a trait as produced by a mutation I simply doubt it, recognizing it as a notion that is required by the competing model of evolution but in reality most likely simply the result of an unusual combination of the pre-existing built-in allelic possibilities that go back to the creation, brought about by many generations of population splittings and consequent reduced genetic diversity which just happened to bring this particular combination to expression.

So, I habitually reinterpret descriptions of traits that ascribe them to mutation, as in this description of the wrinkled skin of the Shar Pei dog for instance:
Scientists from the Department of Genome Sciences at the University of Washington, Seattle, announced in January 2010 that they had analysed the genetic code of 10 different pedigree dog breeds. In the Shar-pei they discovered four small differences located in the gene HAS2 which is responsible for making hyaluronic acid synthase 2. That enzyme makes hyaluronic acid, which is one of the key components of the skin. There have been rare cases in which a mutation of the same gene has caused severe wrinkling in humans as well.[3]
While this MIGHT be a mutation -- a mistake in the replication of the gene -- especially where it produces a clear deformity, it is most likely, according to the creation model, to be simply a case of a rare allele having come to expression in the breed after many generations of isolation and inbreeding.

Is it possible to tell a pre-existing normal nonmutated allele from a supposed mutation as expected by evolution? I don't think so. Mutation is simply assumed, because the theory of evolution requires it.

MACROEVOLUTION
What I'm describing is often called "microevolution" but it's the only kind of evolution that is possible, variation within the species based on the genetic endowment built in at the Creation. No other genetic input is required. For "macroevolution" to occur, however, meaning changes that transcend the Species or Kind, would require genetic input from somewhere, and this is what "mutations" are assumed by evolutionists to provide, but if they are mistakes that confer no benefit on the organism obviously this should be recognized as a dashed hope.

EVOLUTIONIST JUST-SO TALES
Also incidentally found in that same Wikipedia discussion of the Shar-Pei is the typical evolutionist tale that "explains" the survival of a particular feature, in this case the heavily wrinkled skin:
If a Shar Pei is being attacked the wrinkles keep the Shar Pei from being injured badly.[citation needed]
The sort of "explanation" that is meant to account for the persistence of the feature.

Sometimes such factors may indeed apply, but according to my creation model it's more likely that the trait simply emerged in the process of allele shufflings in population isolations over generations and wasn't a detriment so it stuck around. It may confer benefits of course, but these don't have to be the reason for its existence. The creation model produces creative variations kind-of-just-for-the-love-of-them, as it were, just for the "love" of beauty and diversity, they don't need specific reasons that enabled them to survive. So, for instance, rather than Darwin's finches having evolved their characteristic beak styles in order to fit into a niche where the particular beak was suited to the particular food, the creation model would say the finches that just happened to develop with a particular beak style gravitated to that kind of food just because the beak WAS suited to it, and over subsequent generations THEN the beak could have become established and refined for that purpose within that population.

So the idea that the wrinkled skin protects the Shar Pei from injury MAY be true enough (who knows) but it isn't necessary as an explanation for the existence of the trait. This is just the usual imaginative speculation that makes up, oh, 90% of the whole theory of evolution. It even says "citation needed." Well, maybe someone will come up with a citation to a study that seems to prove it, but evolutionists never really require such proof, the ad-hoc speculation explanation alone usually suffices.

Why aren't there any pre-human hominids (or other varieties of hominids) still running around? Oh probably because we killed them all off or ran them off the territory that sustained them and so on and so forth. They publish whole peer-reviewed papers speculating about the reasons and they'll call it science and they'll beat up creationists who continue to demur. They haven't a clue but such "likely stories" seem to be enough to keep them happy. Of course the REAL reason is that there never WERE any pre-human hominids.

How come there is a bone in the whale skeleton fossil where a hip joint would have been located? Oh that's proof that the whale evolved from a land animal. Huge huge leap but because it fits the ToE they enshrine it as ***S*c*i*e*n*t*i*f*i*c*** F*a*c*t***.

But continuing with my Creation Model:

JUNK DNA
Junk DNA is most likely the record of genetic death over the generations due to the Fall, much of it brought about by mutations that simply killed the function of gene after gene. Probably the majority of it is a record of the Great Death brought about by the Flood. If there is some function left in some of them that is all it is, a bit of crippled life that remains, that wsan't completely killed. Those creationists who want to find function in the DNA are not thinking clearly. They feel they have to prove the original perfection of the Creation and forget that the Fall has made enormous changes in the original perfection through destructive processes -- disease, death, deformity -- that had no part in the original.

NATURAL SELECTION
What about Natural Selection? In this creation model NS is one possible way variations develop, but only one of many. Simple migration will succeed at creating a new variation by isolating a new population just as well as NS will, by creating new gene frequencies, just as adapted to its situation as anything NS produces, and without the death that NS often requires. Natural Selection applies mostly to situations where there is an actual survival threat that prevents the creature from passing on its genes, such as when an aggressive predator wipes out much of the population. Some sort of defensive mechanism in a few of the prey population's members may save some of them and therefore be passed on and become characteristic of the new population. A change in the environment, say the food supply, may kill off many members of a particular population but those that have some form of adaptation to the new food situation will pass on their genes. Etc. etc. It no doubt happens, but probably is fairly rare among all the ways new populations develop from genetic variations, perhaps far more often than not simply leading to extinction rather than an adapted variation. Forced adaptation to specific situations can't be as much of a driving force for change as evolution claims. As far as new variations go, genetic drift does the same thing within a population. Bottleneck is simply a drastic version of either migration or natural selection, creating a severely reduced population with severely reduced genetic diversity in a single event. Etc. etc.

FOSSIL RECORD
What is the Fossil Record according to the Creation Model? Obviously it's overwhelmingly to be explained as the remains of the creatures that died in the Flood of Noah. Obviously.

Why is there the seeming gradation of primitive to advanced morphology in the Fossil Record? There really isn't, there is simply a sorting of creatures according to some physical principle, probably many physical principles, that occurred in the Flood. The apparent gradation is an illusion. Differences between different fossil representatives of one species to be found in different layers or different parts of the world simply demonstrate the same principle of variation I'm describing above, not evolution from one type to another. There are lots of different varieties of Trilobites in the Fossil Record for instance, each variety flocking with its own kind, which evolutionists interpret as evolution over time, presumably from less to more advanced types, but all they are really is separate populations of the many possible variations that were built into the original genome of the Trilobite species.

STRATA / GEOLOGIC COLUMN / GEO TIMETABLE
What about the existence of the strata themselves, known as the Geologic Column? Well, that is really a no-brainer. Nothing BUT a worldwide Flood could have brought about those strata. The interpretation of huge time periods attaching to separated sediments is just plain ludicrous. And don't tell me that is a wrong reading of the geo timetable. Just go look at the model of the Grand Canyon where the "time periods" are associated with the different sediments.

And so on and so forth.

The point of this post is to demonstrate that there IS a Creation Model that IS consistent with the actual facts, can account for just about everything the Evolution model attempts to account for and in my opinion way better.

There is much more that could be added here but I'll have to get back to it later or do it in another post.

==============
From Post at EvC:
No one seems interested that the best microbiology has been able to accomplish is 1+1=2.
Ok, 1 +1 =2. Then we're at 2, and 2 + 1 = 3, then we're at 3, and 3 + 1 = 4. Now we're at 4, and 4 + 1 = 5. 5 + 1 = 6. 6 + 1 = 7. 7 + 1 = 8. 8 + 1 = 9. 9 + 1 = 10.

Lots of little changes add up to a big change. What you need to do, to allow micro but deny macro, is come up with some mechanism that stops little changes from accumulating.
Easy. I told them there and I'm arguing here over and over again: THE PROCESSES THAT PRODUCE VARIATIONS / CHANGES IN THE PHENOTYPE / SPECIATION / "EVOLUTION" ULTIMATELY LEAD TO REDUCED GENETIC VARIABILITY OR DIVERSITY, WHICH EVENTUALLY PUTS AN END TO THE POSSIBILITY OF MORE CHANGES. This end point defines the outer limit of a Species or Kind. That's your "mechanism." It should be testable, both in the wild and in a laboratory.

Wednesday, February 29, 2012

Just another Evolutionist PRATT, the usual paradigm-bound misconception of Speciation

Somebody just started a new thread at EvC titled An example of speciation in action? giving an example of reproductive isolation bringing about changes between two separate populations of a bird called a Blackcap. Differences in appearance between the two are minimal but differences in behavior are enough to keep them apart.

This is treated as some kind of wonderful event, at least a step on the way to macroevolution, which makes it just another evolutionist PRATT (Point Refuted a Thousand Times). I for one have answered it over and over both at EvC and on my blog, and I can't be the only one.

All this is merely one of the ways variation naturally occurs in species because of built-in genetic variability. It's nothing more than normal "microevolution," changes that are expected because of this built-in genetic variability, which can come about through anything that isolates a portion of a population from another so that they don't interbreed. Genetic drift within populations even does this but populations may also become physically separated from one another and go on to develop their own characteristics different from each other. This occurs because reproductive isolation brings about different gene frequencies in the new populations as compared to the original population. Really, it's to be expected that reproductive isolation would bring about changes between populations in this way. No mutations need be involved and there's no reason to suppose they are EVER involved.

It's simply a matter of different combinations or frequencies of alleles becoming characteristic in each of the separated populations. This is the natural result of the differences in gene frequencies working their way through each population over a few generations. Over time this brings about changes in the phenotypes characteristic of the new populations as a whole that differentiates them from each other more and more, sometimes to the point of approaching what the evolutionists would be inclined to call speciation. That depends on the degree of genetic variability that remains. The less genetic variability there is compared to the original population the more dramatic its changes will be, and the more likely it is that the populations will develop inability to interbreed with one another.

Is this speciation? This is an arbitrary definitional matter. It doesn't matter at what point population changes get called speciation, whether at this stage of practical differences bringing about lack of opportunity to interbreed, or behavioral disinclination to interbreed, or at the stage when isolation has brought about complete inability to interbreed because of genetic incompatibility, the effect is always that in isolation each population continues to elaborate its own separated gene pool and diverges further from the other.

Again, you don't need mutations to bring this about, merely different frequencies of alleles in each population.

And, as I've argued from the beginning of this blog, the result of these changes over time, especially with further splittings of the populations and further elaborations of the new gene frequencies brought about by the splitting, is reduced genetic variability that makes further evolution less possible, and ultimately impossible. The more evolution you have, the less evolution is possible. Evolution defeats evolution.

Oh well, they don't listen to such obvious simple contradictions of their beliefs. Maybe a creationist will come along and make the point eventually, and they'll ignore that too because they really don't care about science, only about justifying evolution.

But there's a brief statement of it just for the record.

========================
By the way, they often complain that creationists offer no evidence for many interpretations such as the above, without ever recognizing that they have no evidence for their opposing interpretations either, but have only the familiar just-so story line.

They interpret the changes brought about by reproductive isolation as steps in open-ended evolution, simply because that's what the theory requires, not because they have any evidence for it. To their mind the simple fact that such changes do occur IS the evidence -- evidence for the theory of evolution. But there is no evidence for the open-endedness of the change process itself, that's just assumed. Darwin assumed it and it continues to be assumed.

Likewise they assume mutations as the engine that keeps it all going because the theory requires such an engine. You can get different kinds of finches out of the built-in genetic complement that belongs to finches, but you can't get an iguana out of a finch without the input of new genetic material or "information."

So instead of even recognizing that there is such a thing as a built-in genetic complement that defines a species (which is really the definition OF a species or Kind at the genetic level, that elusive definition they keep haranguing us creationists to produce), they assume that ALL genetic material is constantly being created by the processes of mutation and natural selection. Again, there is no evidence for this, they have to assume it because the theory requires it.

As a creationist I interpret the changes brought about by reproductive isolation as the effect of shuffling the frequencies of alleles that belong to the built-in genetic complement for the species. There is a natural limit to the changes possible BECAUSE there is this original complement of genetic potentials that can only be shuffled and reshuffled. It CAN play out to less and less genetic variability down any particular line of variation brought about by reproductive isolation, especially a series of reproductive isolations such as in a ring species. What is called "speciation" is really the result of this reduced genetic variability. New phenotypes develop from new frequencies of genes, but reproductive isolation itself over time reduces the genetic variability. This can produce dramatic new phenotypes, but there is a point that is reached when further variation becomes impossible. You may have a striking new variation (they call it a new species) but it may have such reduced genetic variability it can't change any further at all. Yes, like the cheetah. Thus bringing the processes of evolution to an end for that line of variation.

Mutations are of absolutely no use in this scenario, they only interfere with it, and in reality that does appear to be what happens, which is evidence for the scenario right there -- thousands of genetic diseases, thousands of "neutral" mutations that have simply not produced anything identifiable (although they have to be deleterious because they change the genetic code, which was originally perfect), and a very few known "beneficial" mutations that are highly questionable. These are the facts, although the theory of evolution says the opposite and has to interpret them away, as by claiming the beneficial mutations made the entire genetic code so are therefore hard to detect. The known facts, however, are on the creationist's side.

I have also suggested a scientific test that could prove all this, which is more than the evolutionist side can offer. All they have is theory, elaborated by theory, multiplied by theory, developed by theory and validated by theory. Fantasy in other words. No evidence.

Monday, September 5, 2011

The Genetic Markers of the Flood Bottleneck

Here comes JAR with his usual wrongheaded assertions (no, no evidence here) against the Flood of Noah.
To mention "fossils" when talking about the Biblical Flood is of course simply silly. The Biblical Flood, if it had happened, was far too recent to have anything to do with fossils.
Too recent to have anything to do with fossils? 4500 years isn't enough time? Even though evolutionists claim that fossils are being formed every day in our own time in far more mundane circumstances than the global biblical Flood? Excuse me? The Flood buried bazillions of living things which would have been made into fossils in a lot less time than 4500 years. I've seen discussions, probably creationist of course since evolutionists are committed to not knowing such things, that show the process occurring in a matter of years in caves that drip calcium carbonate. If I find such a discussion I'll post it.
The Biblical Flood myths say that all the critters on land and in the air with the exception of those critters on the fictional ark were killed during a very short period.

If that were true, then every land and air critter living today, plant or animal, would be descended from the few critters on the ark.
Very true and they are.
That would leave a genetic bottleneck marker in EVERY single living species of plant of animal, and the marker would be only a relatively few generations back.

If the Biblical Flood happened, then that marker MUST be there.

It ain't.

Case closed.
I've heard this bit of evolutionist lore many times by now, but I have NEVER ONCE SEEN AN EXPLANATION OF EXACTLY WHAT "MARKER" WOULD POINT TO A BOTTLENECK. Perhaps I merely missed it but I've been looking for some time whenever this subject comes up and all that's offered is this assertion, perhaps some ridicule and choice epithets along with it, BUT NO CLUE AS TO WHAT THE MARKER MIGHT BE THAT WOULD DEMONSTRATE THE BOTTLENECK IN QUESTION.

Now that it's come up again perhaps I'll be motivated to make a more dogged search for such information.

But meanwhile I wanted to highlight JAR's post because of something I just learned about these things that opens up a new answer to the question. I've been rereading Morris and Parker's What Is Creation Science? over the last few days, one of the first books on creationism I read after becoming a Christian, and besides recognizing many points they make that I've made my own in this debate although I'd forgotten their source, I've also run across some points that illuminate some things I hadn't digested and am only now beginning to think about.

One of them suggests an answer to just what WOULD be the genetic indicators of the bottleneck at the Flood and they aren't the sort of "marker" that would jump out at you but something a geneticist today would simply take for granted as the normal state of the genome. Whenever I've gone that far into this part of the debate I find myself wondering about a formerly much bigger genome --polyploidy for instance, which never really fit but now I have a better understanding anyway -- from which it would be easier to imagine descent of all the life forms we see today and extravagantly more varieties before the Flood as well, which certainly must have been the case BECAUSE of such an extreme bottleneck.

No, not a bigger genome, but a different genetic situation along more ordinary lines:

Parker describes how all the varieties of humans and animals are easily accounted for by simple Mendelian genetics combining a given built-in array of genes for various traits. The example he gave was of two parents with "medium" or "average" skin color, expressed as AaBb, with the capital letters representing the darkest and the lower case the lightest, saying that EVERY shade of skin that we see on earth can be produced from those two parents, from the darkest African (AABB)to the lightest Scandinavian (aabb). When you think of every other trait as genetically expressed by the same formula, it becomes clear that an enormous variety of combinations would produce an enormous variety of types or varieties or races -- of people and animals of all kinds -- which would become characteristic of groups as they migrated and became geographically isolated from one another.

And all this incredible variety requires is normal sexual recombination AND HETEROZYGOSITY of the traits.

He also gave this statistic on page 112: "[evolutionist Francisco Ayala] says that human beings are "heterozygous" for 6.7% of their genes, on the average. That means that 6 or 7 times in a 100, the pair of genes for a given trait differ like the genes for brown or blue eyes, or for rolling or not rolling the tongue. Now this may not seem like much. But Ayala calculates a single human couple with just "6.7% variety" could produce 10 to the 2,017 children ...before they would have to produce an identical twin..."

He goes on to say that the whole spectrum of skin color we see today would be easily produced IN ONE GENERATION with just this 6.7% heterozygosity for that trait. Combining that with the same breadth of possibilities for size, hair or fur color, bone type, muscle type, and so on and so forth, would certainly yield an enormous variety of individuals within each created kind or type.

So I figure this 6.7% heterozygosity is what remained on average to all creatures after the Flood, or perhaps it was somewhat more then and has decreased since then. It's still enough to produce enormous variety, everything we see today.

Well, what does a bottleneck do genetically anyway? Doesn't it produce HOMOZYGOSITY for a number of traits? Isn't that what happened to the cheetah -- it has reached the point genetically where most of its genes are fixed and no variety is possible at all. Since the cheetah is of course descended from the cats on the ark, with their already drastically reduced heterozygosity -- perhaps comparable to the 6.7% of human beings -- a later bottleneck would have reduced it even further to the current state of almost 100% fixed loci, so that each individual is almost a clone of all the others, and further variation is as good as impossible.

THERE'S YOUR "MARKER" JAR. Not what you were expecting but there it is. It wouldn't be recognizable in the genome because nobody is looking for it. The average heterozygosity seen today would be accepted as the norm for all human beings for all time. It wouldn't be suspected as a marker of anything, although the basic principle is quite well known.

So instead of the genetic complexities I was trying to imagine to account for the necessity of an enormously greater variety among humans and animals before the Flood, I now appreciate that simple ordinary everyday heterozygosity can account for it all, but presumably there would have been much MORE heterozogosity for a much greater number of genes or traits before the Flood. 100% back at Adam and Eve? 50%?

And to that I would like to add another "marker" of the bottleneck, one of my favorite topics, JUNK DNA -- which makes up something over 90% of the genome. You wouldn't suspect that as a sign of the bottleneck at the Flood, would you, JAR? But if it's what I keep thinking it must be, the record of the genetic death brought about by that bottleneck, as well as all the accumulated death from other causes of course, then its mere existence in the genome is very glaring evidence of the Flood, now to be added to the other marker, the very low incidence of heterozygosity that resulted from all that death. This genetic junkyard or graveyard is a hint at enormously more genetic possibilities at the Creation than exist today.

May I please have my Nobel Prize now?

Sunday, November 7, 2010

Once again: The natural processes that bring about "evolution" have a natural end point

Another round proposed to address the ongoing question, What prevents micro evolution from becoming macro evolution?

This is what I argued at EvC off and on from my very first post: What is called "evolution" is merely the variations that occur in species of living things from generation to generation, a phenomenon which has been known from the beginning of history and exploited by farmers and husbandmen all that time to maximize chosen qualities in their animals and plants.

Yet a century and a half ago some decided to pretend this well-known phenomenon isn't limited to each of the species but is open-ended so that species may keep on varying into other species over time. The same processes that ALWAYS brought about the variations, simple sexual reproduction for starters but also selection processes that isolate portions of a population from the rest, including what came to be called Natural Selection, were now made to justify the claim that all species come from former species.

As I've said before here many times, this is an hypothesis, fine, but it cannot be proved and has never been proved.

As for the question what prevents micro-evolution from becoming macro-evolution, it's the simple fact, a fact which is testable and falsifiable, that the processes that bring about new variations require the elimination of competing genetic potentials until a particular "evolving" line of a population may end up quite a striking variation in itself, highly specialized but with no further ability to evolve at all, even with fixed loci and no ability to breed with the mother population, no genetic options to develop in its own line.

Soon as someone gets around to making the necessary test, either in the field or in the laboratory, I have no doubt this will be demonstrated.

Meanwhile, yes, it is just an hypothesis, just as their answer is: oh but MUTATIONS enter in to prevent this kind of dead-end fixation of genetic variation. Based on what? On observation? Nope, never seen this, it's merely assumed. On testability? Nope. Just stuff with bacteria that have not been shown to have any bearing on this development in sexually reproducing animals. Nope, it's all purely hypothetical, yet as usual they assert it as if it were fact.

The fact is that IF mutations DID keep interfering with the isolating processes that are necessary to developing new variations / or species, you'd never GET new variations or species, you'd just get a continuing hodgepodge of genes that keep on blending back into the general species characteristics and never differentiating. NOT evolution.

Nope, the natural processes that bring about variation -- mistaken for open-ended evolution -- NATURALLY lead to genetic depletion. Conservationists know this only too well and it is an endless headache to them. It's the natural built-in mechanism for variation to occur within species but undesirable as well as desirable variations may be the result of random natural processes.

If death had never entered the world back in Eden, life forms would simply continue to vary and genetic depletion would not be a problem, merely a mechanism for variation, exhibiting the creative potentials of life in wondrous ways. But since death entered, all life is gradually approaching extinction -- some ways off yet I trust -- and the natural isolating processes that bring about variations only speed up its approach.

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That's my answer and I stand by it. But here's another on that same thread I link above, from another creationist, who takes them up on their mutations theory:
I'll put it in the most basic form I can think of.
Both groups observe Mutations happening. Both group realize that these muations are copying errors during the transcription of the genetic code.

Both groups will observe that some of these mutations will become fixed in a population. This is what both will call micro-evolution

Both group will observe that therefore, these copying errors will accumulate in a population, driven sometimes by factors such as natural selection, but also sometimes simply through genetic drift.

But each group has a different opinion on the eventual outcome of all this accumulation of mutations:

- Neo-Darwinian evolutionists will say that these will accumulate to the point that new features, organs, etc. will appear in the population, showing an ever evolving and changing trend in biological populations. This is what they will cal macro-evolution.

- Creationists will say that these will accumulate to the point that the mutational burden will become much too high, and this will lead the population down a spiralling path to genetic meltdown. Macro-evolution will therefore never happen.

Creationist will often complain when evolutionist use examples of micro-evolution to prove that macro-evolution will happen, because it simply does not discard the possibility that accumulating mutations could lead to genetic meltdown.
Translation: To the extent that mutations ARE observed happening, they do not supply the kind of positive variations that evolutionists assume (and cannot demonstrate). The actual evidence is that mutations overall play a destructive role, either by replacing a functioning part of the genetic code with non-coding gobbledygook, or by actually coding for something harmful. Very very occasionally the harmful change may happen to have a beneficial side effect but it's always a trade-off. This is not the kind of upward-and-onward life vigor that the theory of evolution requires. In other words, one way or another mutations only contribute to the death processes that the Fall introduced.

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And along come the evolutionist answers of course:

Starting with Percy :
This isn't an accurate characterization of what evolutionary biologists say. Through natural selection, deleterious mutations are removed and advantageous mutations retained. It is advantageous mutations (and to be more complete, also mostly neutral mutations) that accumulate, not all mutations.
- Creationists will say that these will accumulate to the point that the mutational burden will become much too high, and this will lead the population down a spiralling path to genetic meltdown. Macro-evolution will therefore never happen.
Because your characterization of the position of evolutionary biologists was incomplete, this characterization of the position of creationists fails to address the fact that deleterious mutations are removed from populations by natural selection and are not included among the mutations that accumulate.
Sure sounds good in theory. In actuality it appears that genetic diseases accumulate in the population faster than they are removed. And that is just a partial list of all the genetic diseases too.
There are thousands of genetic disorders in humans. Some are common whereas quite a few are rare. Whatever be their incidence, what is most vexing about these disorders is that scientists are still trying to find cures for these disorders. While some headway has been made in the direction, a lot more research is required.
THOUSANDS. THOUSANDS. Documented thousands of deleterious mutations that DIDN'T get selected out and continue to plague their possessors. And meanwhile the notion that it's the advantageous mutations that accumulate as Percy states above, has NO evidence for it WHATEVER, it is purely an assumption based on the theory that says it must be that way. Another Hypothesis that cannot be tested, alas.

But all those genetic diseases are sure a reality. Wonder how that happened if it's advantageous mutations that accumulate but deleterious ones don't? Oh I'm sure they have a rationalization, of course, they're good at that, but the plain facts OUGHT to make the party line spelled out above a laughing stock.

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But then Wounded King comes through with some common sense and agrees with what I say above, that the reality doesn't meet the theory as Percy states it, a common sense he does occasionally show in spite of his diehard evolutionist commitment:
[Percy] Because your characterization of the position of evolutionary biologists was incomplete, this characterization of the position of creationists fails to address the fact that deleterious mutations are removed from populations by natural selection and are not included among the mutations that accumulate.
[WK] I'm not sure why you think this. There is plenty of pop. gen. and comparative genetic evidence for fixation of deleterious mutations. Certainly the trends for beneficial and deleterious mutations are as you desribe, but in the real world there is plenty of evidence of deleterious mutations accumulating.

The real question is, as Slevesque posits, whether such mutations are balanced by compensating beneficial mutations or conversely whether organismal fitness is in an irreversible decline, for which there is no evidence except in some organisms with drastically reduced population sizes.
At least there IS that evidence, and as I keep saying it would not be hard to get the evidence that it is generally the case wherever selection and isolating processes are operating, however less drastically. Collect a good number of samples from various populations of a ring species, or set up your own ring species in a laboratory, and look at their DNA, and you'll get the necessary evidence. But at least there IS that much evidence from the drastically reduced populations, and there is NO evidence WHATEVER that BENEFICIAL mutations accumulate, NONE NONE NONE NONE NONE. ALL they have is the THEORY which tells them that they MUST and they believe it to the point of declaring that it actually occurs in reality when there is NO evidence for it. They will call creationists all kinds of names for suggesting that they don't have evidence because they really have deluded themselves that they do.

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Then WK goes on to chide the creationist for not getting all his terminology accurate. Oh come on, if you want to talk to molecular biologists then stop talking to creationists, we do the best we can to get the terminology straight, and beyond that it's your obligation as the expert to translate if necessary. We'll learn that way but not by being told we have to get a degree in the relevant science first. It's clear that you DO understand what slevesque was saying and are only nitpicking about the words to pull rank. The important thing is the topic. Clarify if you really don't understand, but it's clear that you do, WK, so cut the guff.

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And a last point for this thread: Coyote chimes in mentioning a creationist, Sanford, who argues that the genome is deteriorating. I didn't know about this man, but obviously he is on the right track. If I can ever afford it I'll get his book, but that will be a while the way things are going lately.

Here's the Wikipedia article on John C. Sanford :
Sanford has written a book entitled Genetic Entropy & the Mystery of the Genome (2005)[3] in which he claims that the genome is deteriorating and therefore could not have evolved in the way specified by the Modern evolutionary synthesis. Sanford's claims have received little attention from the scientific community. Sanford has published two peer reviewed papers modeling genetic entropy.[4][5]
And here's his book at Amazon . There's a great review of it by someone who calls himself Saint and Sinner, posted in December 2006. Here's an excerpt:

Chapter 2
Here is where we start getting into the analysis of NDET [Neo-Darwinian Evolutionary Theory]. Sanford discusses the statistical distribution of mutational effects (i.e. the magnitude of good and bad mutations affecting fitness) and their frequency. Sanford points out a number of differences between NDET and reality:

A. NDET posits that most mutations are neutral. However, Sanford argues that there is no such thing as a truly "neutral" mutation. Rather, most mutations are "near-neutral" (whether increasing fitness or decreasing fitness). Even a single point-nucleotide mutation in a minor area of the genome disrupts the genetic code to some degree (no matter how small). This is key for the rest of his book.

B. The naïve view of mutational distribution is a bell curve (though many Darwinists recognize that the actual distribution found in nature is nothing like it). The real distribution is a Kimura curve (named after the *Darwinist* population geneticist who created it) where the *vast* majority of the curve is near-neutral. Sanford notes that if the normal distribution (i.e. "bell curve") was true, then an increase in complexity would be inevitable. However, with the Kimura curve, it is hard to see any substantial increase in fitness "getting off the ground" so-to-speak. [note: "naive" means theoretical, hypothetical, pure assumption, untested; "real" means what has been observed in reality. Clearly tons of evolutionary theory is a mere assumption or reification of theory that is untested. AS I KEEP SAYING.]

C. NDET acknowledges that most mutations are harmful, but doesn't suggest that the ratio is so small as to never allow an increase in fitness that would affect a population. Contrary to that assumption, the actual ratio, as noted by the population geneticists (most of whom are Darwinists!) whom Sanford cites, is so small that population geneticists don't even place the beneficiary curve on the distribution graph! The ratio that Sanford cites (again, from the population geneticists) is between 10,000 to 1,000,000 harmful mutations for every one beneficial (though probably closer to the former figure rather than the latter). Sanford chooses to be conservative, and for the rest of the book, he assumes the 10k ratio. Keep this in mind when the next point is cited.

D. NDET assumes that natural selection will take out all of the bad mutations and leave only the good (notice that that was a near quote of Darwin himself). However, citing the population geneticist, Kimura, for support, Sanford notes that there is a "zone of near-neutrality" on both the beneficial and harmful sides of the curve in which natural selection doesn't select for or against. This is due to the fact that most mutations are point-nucleotide mutations. These only cause an ever-so-slight decrease in fitness that natural selection can't "see" them 99% of the time. It would be like a single pixel on your television screen going out. Would you really be able to tell a difference? Furthermore, since the beneficiary mutations curve is so small (see point C. above), the "zone of near-neutrality" (a.k.a. the "no-selection box") covers 99% of the beneficiary mutation side of the distribution! This ensures that natural selection will never see 99% of the good mutations while allowing the bad (which are vastly greater in number) to accumulate. Thus, the genome will suffer from "genetic entropy" (and hence the title of the book).

Now, a typical reply (which is, in fact, found below in one of the negative reviews) is that biologists have witnessed and documented such beneficiary mutations that have given great benefit to organisms in their environment. However, many biologists are becoming aware that the vast majority of these changes in phenotype are due to "pre-programmed" changes in the genome, not random ones as NDET demands. Secondly, as Sanford points out in Appendix 4, many of these "beneficial" mutations actually end up giving the organism a net decrease in fitness (as in the case of homeostasis in cold-climate creatures to warm climates or drug-resistant bacteria) making them deleterious in reality!

Sounds to me like Sanford is right on, the bias-blinded Scientific Community's prejudices notwithstanding.

Wednesday, November 18, 2009

Allele Frequencies

Here's a discussion of changes in allele frequencies at Wikipedia
Population genetics studies the different "forces" that might lead to changes in the distribution and frequencies of alleles -- in other words, to evolution. Besides selection, these forces include genetic drift, mutation and migration.
In other words, Richard Dawkins' repeated refrain, "Evolution by Natural Selection" isn't current any more, as I'd thought.

Tuesday, November 17, 2009

Famous model for different types of speciation:




I'll be back to discuss it.

While I'm gone, ponder it. Don't just accept the evolutionist idea of it.




Wikipedia Reference